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Anti-CEBP Alpha Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CEBP Alpha rabbit polyclonal antibody |
Gene Name: | CCAAT/enhancer-binding protein alpha |
Synonyms: | CEBPA, C/EBP-alpha, CEBP, CRP1, C/EBP epsilon |
Immunogen: | Recombinant protein corresponding to Mouse CEBP Alpha |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 37 KDa |
Observed MW. | 43 KDa |
Uniprot ID: | P49715, P53566, P05554 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 800-1: 1000 | liver, lung, adipose |
Background
CCAAT/enhancer-binding protein alpha is a transcription factor involved in the differentiation of certain blood cells. The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers.The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Images
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Western blot analysis of CEBPa (GB11538) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
