Reactivity: | R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CIKS/ACT1 rabbit polyclonal |
Gene Name: | E3 ubiquitin ligase TRAF3IP2 |
Synonyms: | ACT1, Adapter protein CIKS, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, Connection to IKK and SAPK/JNK, TRAF3 interacting protein 2, TRAF3IP2 |
Immunogen: | Recombinant protein corresponding to Mouse CIKS/ACT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm, Secreted |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 1800-1: 3600 | spleen |
Background
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified.
Images
Immunohistochemistry analysis of paraffin-embedded rat spleen using CIKS/ACT1 (GB113480) at dilution of 1: 3600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |