Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CLASP2 rabbit polyclonal |
Gene Name: | CLIP-associating protein 2 |
Synonyms: | CLASP2, CLIP associating protein 2, hOrbit2, KIAA0627, Protein Orbit homolog 2, Cytoplasmic linker-associated protein 2 |
Immunogen: | Recombinant protein corresponding to Mouse CLASP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 141 kDa |
Observed MW. | 160 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 1000 | brain |
Background
CLASP2 (CLIP-associating protein 2) is a brain specific protein belongs to CLASP family. CLASP1 and CLASP2 regulate microtubule plus-end dynamics in brine cortex. CLASP2 is required for the orientation of stabilized microtubules toward the leading edge, It may act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms. Phosphorylation of CLASP2 by GSK3B may negatively regulate binding to microtubule lattices in lamella.
Images
Western blot analysis of CLASP2 (GB113456) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |