Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CLCA1 rabbit polyclonal antibody |
Gene Name: | Calcium-activated chloride channel regulator 1 |
Synonyms: | Calcium-activated chloride channel family member 3, mCLCA3, Protein gob-5, Clca3, Gob5, Clca1 |
Immunogen: | Recombinant protein corresponding to Mouse CLCA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | Q9D7Z6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 700-1: 1400 | colon, duodenum |
Background
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.
Images
Immunohistochemistry of paraffin embedded mouse colon using CLCA1 (GB112315) at dilution of 1:700 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse duodenum using CLCA1 (GB112315) at dilution of 1:700 (400x lens) | |
Immunohistochemistry of paraffin embedded rat colon using CLCA1 (GB112315) at dilution of 1:700 (400x lens) | |
Immunohistochemistry of paraffin embedded rat duodenum using CLCA1 (GB112315) at dilution of 1:700 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |