Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Claudin domain-containing protein 1 |
Synonyms: | C3orf4, GENX 3745, Claudin domain containing 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CLDND1 |
Uniprot ID: | Q9CQX5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 29 kDa / 29 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain |
Background
CLDND1 is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Images
Western blot analysis of CLDND1 (GB115402) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |