Reactivity: | H,R & H |
Applications: | WB & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Chloride intracellular channel protein 4 |
Synonyms: | mc3s5/mtCLIC, Clic4, Intracellular chloride ion channel protein p64H1, mtCLIC, p64H1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CLIC4 |
Uniprot ID: | Q9QYB1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 29 kDa / 29 kDa |
Product Usage Information
WB | Human, Rat | 1: 400-1: 800 | kidney, ovary |
ICC/IF | Human | 1: 50-1: 200 | Hela |
Background
Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.
Images
Western blot analysis of CLIC4 (GB112388) at dilution of 1: 400 | |
Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using CLIC4(GB112388) at dilution of 1: 50-1: 200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |