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Anti-CLIC6 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CLIC6 rabbit polyclonal antibody |
Gene Name: | Chloride intracellular channel protein 6 |
Synonyms: | Clic6, Parchorin, CLIC1L, hloride channel form A |
Immunogen: | Recombinant protein corresponding to Mouse CLIC6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | Q96NY7, Q8BHB9, Q811Q2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:300-1:600 | brain, breast cancer, Cholangiocarcinoma, eye, lung, lung cancer, placenta, uterus |
Background
CLIC6 (chloride intracellular channel 6) is believed to play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. The CLIC6 gene is a rare example of large-scale segmental paralogy in which a large (approximately 500 kb) segment on human chromosome (HC) 21 (21q22) is triplicated on HC 1 and HC 6. CLIC6 is also known to interact with dopamine receptors DRD2, DRD3 and DRD4.
Images
| Immunohistochemistry analysis of paraffin-embedded human lung using CLIC6 (GB112593) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded mouse lung using CLIC6 (GB112593) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded rat lung using CLIC6 (GB112593) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded human placenta using CLIC6 (GB112593) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin-embedded rat placenta using CLIC6 (GB112593) at dilution of 1: 600 |
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Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
