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Anti-COX2 / Cyclooxygenase 2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Cyclooxygenase 2 rabbit polyclonal antibody |
Gene Name: | Prostaglandin G/H synthase 2 |
Synonyms: | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, prostaglandin-endoperoxide synthase 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Cyclooxygenase 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 69 kDa |
Observed MW. | 74 kDa |
Uniprot ID: | Q05769, P35355 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | spleen+LPS, lung+LPS, thymus |
Background
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression.It is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS, a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Images
| Western blot analysis of Cyclooxygenase-2 (GB111037) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
