Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Cytochrome c oxidase subunit 7B, mitochondrial |
Synonyms: | COX7B |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse COX7B |
Uniprot ID: | P56393 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion inner membrane |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 800-1: 2400 | liver cancer, liver, colon, kidney, heart, pancreas |
Background
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.
Images
Immunohistochemistry analysis of paraffin embedded human liver cancer using COX7B (GB115181) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded human liver using COX7B (GB115181) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded mouse colon using COX7B (GB115181) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded mouse kidney using COX7B (GB115181) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded rat heart using COX7B (GB115181) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded rat pancreas using COX7B (GB115181) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |