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Anti-CPI-17 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CPI-17 rabbit polyclonal antibody |
Gene Name: | Protein phosphatase 1 regulatory subunit 14A |
Synonyms: | 17 kDa PKC-potentiated inhibitory protein of PP1, Protein kinase C-potentiated inhibitor protein of 17 kDa, CPI-17, Ppp1r14a, Cpi17CPI17 alpha , PPP1INL, Regulatory subunit 14A |
Immunogen: | Recombinant protein corresponding to Mouse CPI-17 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 17 kDa |
Observed MW. | 17 kDa |
Uniprot ID: | Q91VC7, Q99MC0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | colon, lung, brain |
IHC/IF | Mouse, Rat | 1: 700-1: 2000 | brain, cerebellum |
Background
PPP1R14A, also named as CPI17, belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. CPI17 has two isoforms:CPI-17alpha (17 kDa) and CPI-17beta (13 kDa).
Images
| Western blot analysis of CPI-17 (GB111679) at dilution of 1: 1000 Lane 1: Mouse colon tissue lysate Lane 2: Mouse lung tissue lysate Lane 3: Rat brain tissue lysate Lane 4: Rat colon tissue lysate |
| Immunohistochemistry analysis of paraffin-embedded mouse hippocampus using CPI-17 (GB111679) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded rat hippocampus using CPI-17 (GB111679) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse placenta using CPI-17 (GB111679) at dilution of 1: 2000 |
 | Immunohistochemistry analysis of paraffin-embedded rat placenta using CPI-17 (GB111679) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
