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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CREB rabbit polyclonal antibody |
Gene Name: | Cyclic AMP-responsive element-binding protein 1 |
Synonyms: | CREB-1, CAMP-responsive element-binding protein 1, CAMP responsive element binding protein 1, Active transcription factor CREB |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CREB |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 37 kDa |
Observed MW. | 43 kDa |
Uniprot ID: | Q01147, P15337 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex, cerebellum, spinal cord |
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Images
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Western blot analysis of CREB (GB111052) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
