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| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CREB rabbit polyclonal |
Gene Name: | Cyclic AMP-responsive element-binding protein 1 |
Synonyms: | CREB1, CREB, CREB-1, cAMP responsive element binding protein 1, Transactivator protein, Active transcription factor CREB |
Immunogen: | Recombinant protein corresponding to Mouse CREB |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1:1000-1:2000 | tonsil, lung cancer, colon cancer, kidney, brain |
IF | Human, Mouse, Rat | 1:500-1:2000 | tonsil, lung cancer, colon cancer, kidney, brain |
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Images
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Immunohistochemistry analysis of paraffin-embedded human tonsil using CREB (GB11539) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using CREB (GB11539) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded human colon cancer using CREB (GB11539) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse kidney using CREB (GB11539) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse heart using CREB (GB11539) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse heart using CREB (GB11539) at dilution of 1:1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
