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Anti-CRIF1 Rabbit pAb (100 μl)
| Reactivity: | M,R & H |
| Applications: | WB & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Growth arrest and DNA damage-inducible proteins-interacting protein 1 |
Synonyms: | 39S ribosomal protein L59, mitochondrial, MRP-L59, Gadd45gip1, CKbetaBP2, CKII beta binding protein 2, G45IP_HUMAN, p53 responsive gene 6, L2-interacting nuclear protein 1, Papillomavirus |
Immunogen: | Recombinant protein corresponding to Mouse CRIF1 |
Uniprot ID: | Q9CR59 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 26 kDa / 25 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | liver, spleen, lung |
ICC/IF | Human | 1: 100-1: 400 | Hela |
Background
GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Images
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Western blot analysis of GADD45GIP1 (GB111592) at dilution of 1: 500 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using CRIF1(GB111592) at dilution of 1: 100-1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
