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Anti-CTLA4 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CTLA4 rabbit polyclonal antibody |
Gene Name: | Cytotoxic T-lymphocyte protein 4 |
Synonyms: | Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4, ALPS5, CELIAC3, GRD4, GSE, ICOS, IDDM12 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CTLA4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 25 kDa |
Observed MW. | 25 kDa |
Uniprot ID: | P09793 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | spleen, lung |
Background
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
Images
| Western blot analysis of CD152 (GB111877) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
