Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CTNNA1 rabbit polyclonal antibody |
Gene Name: | Catenin alpha-1 |
Synonyms: | 102 kDa cadherin-associated protein, Alpha E-catenin, CAP102, Ctnna1, Catna1 |
Immunogen: | Recombinant protein corresponding to Mouse CTNNA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 100 kDa |
Observed MW. | 100 kDa |
Uniprot ID: | P35221, P26231 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | uterus, brain |
Background
CTNNA1 is a member of the b-catenin family of cytosolic proteins. Alpha catenin interacts with N-cadherin and b-catenin on the cytosolic side of adherins junctions to mediate the interaction with the actin cytoskeleton. Alpha catenin is a homodimer in solution, but dissociates to form a 1:1 heterodimer with b-catenin in order to interact with cadherins. It also regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Alpha catenin also functions in the control of the startle modulation.
Images
Western blot analysis of Catenin-alpha-1 (GB111268) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |