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Anti-CTP synthase/CTPS Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CTP synthase/CTPS rabbit polyclonal antibody |
Gene Name: | CTP synthase 1 |
Synonyms: | CTP synthetase 1, UTP--ammonia ligase 1, Ctps1, Ctps, Cytidine 5 prime triphosphate synthetase |
Immunogen: | Recombinant protein corresponding to Mouse CTP synthase/CTPS |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 67 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | P17812, P70698 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | kidney, skin |
Background
There are two genes encoding members of a new family of type II integral membrane proteins. Both are ubiquitously expressed, and tissue-specific alternative mRNA initiation and splicing generate at least two major isoforms of each protein, with the smaller isoforms being truncated at the N-terminus. These proteins are called nesprin-l and -2 for nuclear _envelope _spectrin repeat, as they are characterized by the presence of multiple, clustered spectrin repeats, bipartite nuclear localization sequences and a conserved C-terminal, single transmembrane domain. Transient transfection of EGFP-fusion expression constructs demonstrated their localization to the nuclear membrane with a novel C-terminal, TM-domain-containing sequence essential for perinuclear localization.
Images
| Western blot analysis of CTPS (GB111778) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
