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Anti-Cullin 4B/CUL-4B Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Cullin 4B/CUL-4B rabbit polyclonal antibody |
Gene Name: | Cullin-4B |
Synonyms: | CUL-4B, Cul4b, mKIAA0695, MRXHF2, MRXS15, MRXSC, SFM2 |
Immunogen: | Recombinant protein corresponding to Mouse CUL-4B |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | A2A432 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 300-1: 1200 | brain, heart, placenta, small intestine, testis |
Background
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
| Immunohistochemistry of paraffin embedded mouse brain using CUL4B (GB112318) at dilution of 1:750 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse placenta using CUL4B (GB112318) at dilution of 1:750 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using CUL4B (GB112318) at dilution of 1:750 (400x lens) |
| Immunohistochemistry of paraffin embedded rat heart using CUL4B (GB112318) at dilution of 1:300 (400x lens) |
| Immunohistochemistry of paraffin embedded rat small intestine using CUL4B (GB112318) at dilution of 1:300 (400x lens) |
| Immunofluorescence of paraffin embedded mouse testis using CUL4B (GB112318) at dilution of 1:300 (300x lens) |
| Immunofluorescence of paraffin embedded mouse brain using CUL4B (GB112318) at dilution of 1:300 (400x lens) |
| Immunofluorescence of paraffin embedded mouse placenta using CUL4B (GB112318) at dilution of 1:300 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
