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| Reactivity: | M,R & H,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CYC1 rabbit polyclonal antibody |
Gene Name: | Cytochrome c1, heme protein, mitochondrial |
Synonyms: | Complex III subunit 4, Complex III subunit IV, Cytochrome b-c1 complex subunit 4, Cytochrome c-1, Cyc1, QCR4 |
Immunogen: | Recombinant protein corresponding to Mouse CYC1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Predicted MW. | 35 kDa |
Observed MW. | 35 kDa |
Uniprot ID: | P08574, Q9D0M3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 1000-1: 3000 | heart, brain, skeletal muscle, kidney |
IHC/IF | Human, Rat | 1: 400-1: 1200 | kidney, placenta |
Background
CYC1, also named as Cytochrome c-1, belongs to the cytochrome c family. Cytochrome c1 is one respiratory subunit of the 11 subunits of the cytochrome bc1 complex of the mitochondrial electron-transfer chain. It mediates the transfer of an electron from Rieske iron-sulfur protein to cytochrome c. CYC1 mediates apoptosis. In this pathway, a variety of apoptotic stimuli cause CYC1 release from mitochondria, which in turn induces a series of biochemical reactions that result incaspase activation and subsequent cell death.
Images
| Western blot analysis of Cytochrome-c1 (GB111784) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded human placenta using Cytochrome-C1 (GB111784) at dilution of 1: 1200 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat kidney using Cytochrome-C1 (GB111784) at dilution of 1: 1200 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
