Reactivity: | H,M,R & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CYP20A1 rabbit polyclonal antibody |
Gene Name: | Cytochrome P450 20A1 |
Synonyms: | Cyp20a1, CYPM, Cytochrome P450 monooxygenase, Cytochrome P450 |
Immunogen: | Recombinant protein corresponding to Mouse CYP20A1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Predicted MW. | 52 kDa |
Observed MW. | 52 kDa |
Uniprot ID: | Q6UW02, Q8BKE6, Q6P7D4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 250-1: 500 | liver, kidney, testis |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | kidney |
Background
CYP20A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D, E)T, suggesting that its substrate may carry its own oxygen.
Images
Western blot analysis of CYP20A1 (GB112287) at dilution of 1: 250 | |
Immunohistochemistry of paraffin embedded human kidney using CYP20A1 (GB112287) at dilution of 1: 700 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse kidney using CYP20A1 (GB112287) at dilution of 1: 700 (400x lens) | |
Immunohistochemistry of paraffin embedded rat kidney using CYP20A1 (GB112287) at dilution of 1: 700 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |