Reactivity: | M,R & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Cadherin-16 |
Synonyms: | Kidney-specific cadherin, Ksp-cadherin, Cdh16, Cadherin 16 KSP cadherin, Cadherin kidney |
Immunogen: | Recombinant protein corresponding to Mouse Cadherin 16 |
Uniprot ID: | O88338 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 90 kDa / 130 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | kidney |
IHC/IF | Human, Mouse, Rat | 1: 2000-1: 4000 | kidney |
Background
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins.
Images
Western blot analysis of cadherin 16 (GB12935) at dilution of 1: 1000 | |
Immunohistochemistry of paraffin embedded human kidney using cadherin16 (GB12935) at dilution of 1: 2000 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse kidney using cadherin16 (GB12935) at dilution of 1: 2000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat kidney using cadherin16 (GB12935) at dilution of 1: 2000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |