Reactivity: | M,R & M,R & M,R |
Applications: | WB & IHC & IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Cadherin-16 |
Synonyms: | Kidney-specific cadherin, Ksp-cadherin, Cdh16, Cadherin 16 KSP cadherin, Cadherin kidney |
Immunogen: | Recombinant protein corresponding to Mouse Cadherin 16 |
Uniprot ID: | O88338 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 90 kDa / 130 kDa |
Images
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | kidney |
IHC | Mouse, Rat | 1: 1000-1: 2000 | kidney |
IF | Mouse, Rat | 1: 500-1: 1000 | kidney |
Background
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins.
Images
Western blot analysis of Cadherin 16 (GB111318) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse kidney using Cadherin 16 (GB111318) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat kidney using Cadherin 16 (GB111318) at dilution of 1: 2000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse kidney using Cadherin 16 (GB111318) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using Cadherin 16 (GB111318) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |