Anti-Cadherin 16 Rabbit pAb (100 μl)

Applications

Cadherin 16 rabbit polyclonal antibody

Gene Name:

Cadherin-16

Synonyms:

Kidney-specific cadherin, Ksp-cadherin, Cdh16, Cadherin kidney

Immunogen:

KLH conjugated Synthetic peptide corresponding to Mouse Cadherin 16

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Cell membrane

Predicted MW.

90 kDa

Observed MW.

130 kDa

Uniprot ID:

O88338, G3V7L4

Background

This gene is a member of the cadherin super family, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with super family members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development.

Images

	Western blot analysis of cadherin-16 (GB11953) at dilution of 1: 500
	Immunohistochemistry of paraffin embedded mouse kidney using cadherin-16 (GB11953) at dilution of 1: 1500 (250x lens)
	Immunohistochemistry of paraffin embedded mouse kidney using cadherin-16 (GB11953) at dilution of 1: 1500 (300x lens)
	Immunofluorescence of paraffin embedded mouse kidney using cad16 (GB11953) at dilution of 1: 500 (200x lens)
	Immunofluorescence of paraffin embedded mouse nephritis using cad16 (GB11953) at dilution of 1: 1500 (250x lens)

Storage