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Anti-Calpain 9 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Calpain 9 rabbit polyclonal antibody |
Gene Name: | Calpain-9 |
Synonyms: | Digestive tract-specific calpain, New calpain 4, nCL-4, Capn9, Ncl4, CG36 protein |
Immunogen: | Recombinant protein corresponding to Mouse Calpain 9 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 79 kDa |
Observed MW. | 75 kDa |
Uniprot ID: | O14815, Q9D805, O35920 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | stomach |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 1400 | ovary, stomach, uterus |
Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Images
| Western blot analysis of CAPN9 (GB112151) at dilution of 1: 500 |
| Immunofluorescence of paraffin embedded human stomach using CAPN9 (GB112151) at dilution of 1: 700 (300x lens) |
| Immunofluorescence of paraffin embedded mouse stomach using CAPN9 (GB112151) at dilution of 1: 700 (400x lens) |
| Immunofluorescence of paraffin embedded mouse uterus using CAPN9 (GB112151) at dilution of 1: 700 (300x lens) |
| Immunofluorescence of paraffin embedded rat ovary using CAPN9 (GB112151) at dilution of 1: 700 (250x lens) |
| Immunofluorescence of paraffin embedded rat stomach using CAPN9 (GB112151) at dilution of 1: 700 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
