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Anti-Calponin 1 Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Calponin 1 rabbit polyclonal antibody |
Gene Name: | Calponin-1 |
Synonyms: | Basic calponin, Calponin H1, Smooth muscle, Cnn1, Calponin 1 basic smooth muscle, Calponins basic, Sm Calp, SMCC |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Calponin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 33 kDa |
Observed MW. | 36 kDa |
Uniprot ID: | Q08091, Q08290 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | uterus, blood vessels, stomach, lung |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | bladder cancer, colon, skin, uterus |
Background
Calponin is a family of actin filament-associated proteins which regulate smooth muscle cell contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Three isoforms of calponin exist: calponin h1 (CNN1) , calponin h2 (CNN2) and calponin 3 (CNN3). CNN1 is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa.
Images
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Western blot analysis of Calponin-1 (GB11954) at dilution of 1: 500 |
 | Immunohistochemistry of paraffin embedded mouse colon using calponin-1 (GB11954) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse uterus using calponin-1 (GB11954) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat skin using calponin-1 (GB11954) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat uterus using calponin-1 (GB11954) at dilution of 1: 1000 (400x lens) |
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Immunofluorescence of paraffin embedded human bladder cancer using calponin-1 (GB11954) at dilution of 1: 500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse uterus using calponin-1 (GB11954) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |