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Anti-Carbonic Anhydrase 3/CA3 Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Carbonic Anhydrase 3/CA3 rabbit polyclonal |
Gene Name: | Carbonic anhydrase 3 |
Synonyms: | CA-III, CA3, CAIII, Car3, Carbonate dehydratase III, Carbonic anhydrase III |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Carbonic Anhydrase 3/CA3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 29kDa |
Observed MW. | 29kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 800 | skeletal muscle, liver |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | skeletal muscle, white fat |
Background
Carbonic anhydrase III (CA3), which belongs to the alpha-carbonic anhydrase family, is a cytoplasmic enzyme that exhibits a relatively low carbon dioxide hydratase activity. It is expressed at a very high level in skeletal muscle, where physical exercise has been shown to increase free radical production. In addition to its carbon dioxide hydratase activity, CA3 has been demonstrated to have a carboxyl esterase activity and phosphatase activity, which suggests that it is a tyrosine phosphatase . CA3 was found to be localized in Type-I muscle fibers and could be used as a marker for abnormal Type-I muscle fibers in several neuromuscular diseases.
Images
| Western blot analysis of CA3 (GB113775) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded human skeletal muscle using CA3 (GB113775) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using CA3 (GB113775) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using CA3 (GB113775) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse white fat using CA3 (GB113775) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat white fat using CA3 (GB113775) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
