Reactivity: | M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Cathepsin Z |
Synonyms: | Ctsz, Cathepsin B2, Cathepsin IV, Cathepsin P, Preprocathepsin P, Carboxypeptidase LB, CTSX |
Immunogen: | Recombinant protein corresponding to Mouse Cathepsin Z |
Uniprot ID: | Q9WUU7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Lysosome |
Predicted MW. / Observed MW. | 34 kDa / 37 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | lung, spleen, lymph node |
IHC/IF | Mouse, Rat | 1: 600-1: 1200 | liver, rectum |
Background
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.
Images
Western blot analysis of Cathepsin Z (GB112171) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded mouse liver using Cathepsin-Z (GB112171) at dilution of 1: 600 | |
Immunofluorescence analysis of paraffin embedded mouse rectum using Cathepsin-Z (GB112171) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |