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| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cyclin-dependent kinase 2 |
Synonyms: | Cell division protein kinase 2, p33 protein kinase, CDK2, CDKN2, CDC28, CDC2A, Cdc2 related protein kinase, p33(CDK2), MPF |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Cdk2 |
Uniprot ID: | P24941 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. / Observed MW. | 34 kDa / 34 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 400-1: 800 | spleen, thymus, lymph node |
IHC/IF | Human, Mouse, Rat | 1: 200-1: 800 | B lymphocytoma, spleen |
Background
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B).
Images
| Western blot analysis of Cdk2 (GB112129) |
| Immunohistochemistry analysis of paraffin embedded human B lymphocytoma using CDK2 (GB112129) at dilution of 1: 350 |
| Immunohistochemistry analysis of paraffin embedded mouse spleen using CDK2 (GB112129) at dilution of 1: 350 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
