Reactivity: | R & R |
Applications: | IHC & IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Claudin 10 rabbit polyclonal |
Gene Name: | Claudin-10 |
Synonyms: | Cldn10, Cldn10a, CLDN10 protein, CPETRL 3, OSP like protein, OSPL |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Claudin 10 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Endoplasmic reticulum |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 800-1: 2000 | kidney |
IF | Rat | 1: 800-1: 1600 | lung, kidney |
Background
Claudin-10 is a 228 amino acid multi-pass membrane protein that belongs to the claudin family and plays an important role in cell-adhesion activity and tight junction-specific events.The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands.
Images
Immunohistochemistry analysis of paraffin-embedded rat kidney using Claudin 10 (GB112257) at dilution of 1: 2000 | |
Immunofluorescent analysis of paraformaldehyde-fixed rat lung using Claudin 10 (GB112257) at dilution of 1: 800 | |
Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using Claudin 10 (GB112257) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |