Reactivity: | H & H |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Claudin 4 rabbit polyclonal antibody |
Gene Name: | Claudin-4 |
Synonyms: | claudin 4, Claudin 4-specific, CLDN4, CPE R, CPE receptor, CPER, CPETR, CPETR1, hCPE R, WBSCR8 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Claudin 4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. | 22 kDa |
Observed MW. | 18-22 kDa |
Uniprot ID: | O14493 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | MCF-7, A-431, PC-3, Caco-2 |
IHC/IF | Human | 1: 1500-1: 3000 | colon cancer |
Background
Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Images
Western blot analysis of Claudin 4 (GB114056) at dilution of 1: 1000 | |
Immunohistochemistry of paraffin embedded human colon cancer using Claudin 4 (GB114056) at dilution of 1: 1500 | |
Immunohistochemistry of paraffin embedded human endometrial cancer using Claudin 4 (GB114056) at dilution of 1: 1500 | |
Immunohistochemistry of paraffin embedded human liver cancer using Claudin 4 (GB114056) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |