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Anti-CstF-50 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CstF-50 rabbit polyclonal antibody |
Gene Name: | Cleavage stimulation factor subunit 1 |
Synonyms: | CF-1 50 kDa subunit, Cleavage stimulation factor 50 kDa subunit, CSTF 50 kDa subunit, CstF-50, CSTF1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CstF-50 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 48 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | Q05048, Q99LC2, Q5BJQ6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver cancer, stomach cancer, testis , liver-paracancerous |
Background
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). The cleavage stimulation factor (CstF) is a polyadenylation factor that helps to specify the site of processing. CstF recognizes the G+U-rich element, a sequence located downstream of the cleavage site. CstF-50 subunit interacts with the COOH-terminal domain of the RNAP II largest subunit (CTD). This subunit may be responsible for the interaction of CSTF with other factors to form a satable complex on the pre-mRNA, and multiple WD domains are required for protein interactions.
Images
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Western blot analysis of CSTF1 (GB111490) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
