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Anti-Cullin 7 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Cullin 7 rabbit polyclonal antibody |
Gene Name: | Cullin-7 |
Synonyms: | Cul7, CUL7, 3M1, KIAA0076, dJ20C7.5, cullin 7, CUL-7 |
Immunogen: | Recombinant protein corresponding to Mouse Cullin 7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 192 kDa |
Observed MW. | 180 kDa |
Uniprot ID: | Q14999, Q8VE73 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, testis |
Background
Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. In vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.
Images
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Western blot analysis of Cul7 (GB111493) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
