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Anti-Cyclin E1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | G1/S-specific cyclin-E1 |
Synonyms: | CCNE1, CCNE, pcyclin E1, Cyclin E1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Cyclin E1 |
Uniprot ID: | Q61457 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 47 kDa / 47 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 200-1: 400 | testis, colon, placenta |
IHC/IF | Human, Mouse, Rat | 1: 100-1: 400 | testis |
Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.
Images
| Western blot analysis of Cyclin E1 (GB111936) at dilution of 1: 400 |
| Western blot analysis of Cyclin E1 (GB111936) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded mouse testis using cyclin E1 (GB111936) at dilution of 1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
