Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Cyclin L1 rabbit polyclonal antibody |
Gene Name: | Cyclin-L1 |
Synonyms: | Cyclin-L, Cyclin Ania-6a, Ccnl1, Ania6a, Ccn1, Cyclin L gamma |
Immunogen: | Recombinant protein corresponding to Mouse Cyclin L1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 60 kDa |
Observed MW. | 55 kDa |
Uniprot ID: | Q9UK58, Q52KE7, Q9R1Q2 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, spleen |
Background
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.
Images
Western blot analysis of Cyclin-L1 (GB112341) at dilution of 1: 500 | |
Western blot analysis of Cyclin-L1 (GB112341) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |