Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CysLT1 rabbit polyclonal antibody |
Gene Name: | Cysteinyl leukotriene receptor 1 |
Synonyms: | CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, Cysltr1, Cyslt1, Cyslt1r, HG55, HMTMF81 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CysLT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 34 kDa |
Uniprot ID: | Q9Y271, Q99JA4, Q924T8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung |
Background
This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer.
Images
Western blot analysis of CYSLTR1 (GB112415) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |