Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Cystatin-B rabbit polyclonal antibody |
Gene Name: | Cystatin-B |
Synonyms: | CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB |
Immunogen: | Recombinant protein corresponding to Human Cystatin-B |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 11 kDa |
Observed MW. | 11 kDa |
Uniprot ID: | P04080 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 1000-1: 2000 | HepG2, MCF-7, A431, A549, HEK293, HCT116, HT29 |
Background
Cystatin B (CSTB), a member of the cystatin superfamily protein, is a stefin that functions as an intracellular thiol protease inhibitor and has been thought to play a role in protecting against the proteases leaking from lysosomes. CSTB plays various functions in a variety of diseases, including epithelial ovarian cancer, colon cancer, and myoclonus epilepsy. Evidence indicates that mutations in CSTB are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Images
Western blot analysis of CSTB (GB112918) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |