Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Keratin, type I cytoskeletal 13 |
Synonyms: | Krt13, KRT13, CK13, K13, WSN2, keratin 13 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CK13 |
Uniprot ID: | P13646 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Secreted, Cytoplasm |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 500-1: 1000 | bladder cancer, tonsil |
Background
Keratin 13 (or cytokeratin 13) is a protein encoded by the KRT13 gene. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Keratin 13 is a type I cytokeratin, it is paired with keratin 4 and found in the suprabasal layers of non-cornified stratified epithelia.
Images
Immunohistochemistry analysis of paraffin embedded human bladder cancer using CK13 (GB12801) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human tonsil using CK13 (GB12801) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |