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Anti-Cytokeratin 18 Mouse mAb (100 μl)
| Reactivity: | H,M,R & H |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Keratin, type I cytoskeletal 18 |
Synonyms: | KRT18, CK-18, CK18, CYK18, K18, keratin 18 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Cytokeratin 18 |
Uniprot ID: | |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. / Observed MW. | 48 kDa / 48 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 2000 | liver |
IHC/IF | Human | 1: 500-1: 1000 | breast cancer, colon, liver, placenta |
Background
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Images
| Western blot analysis of CK18 (GB12232) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human breast cancer using CK18 (GB12232) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human colon using CK18 (GB12232) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human liver using CK18 (GB12232) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human placenta using CK18 (GB12232) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human colon cancer using CK18 (GB12232) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human lung adenocarcinoma using CK18 (GB12232) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human placenta using CK18 (GB12232) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human liver using CK18 (GB12232) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human colon cancer using CK18 (GB12232) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
