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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DDB1 rabbit polyclonal antibody |
Gene Name: | DNA damage-binding protein 1 |
Synonyms: | DDB p127 subunit, Damage-specific DNA-binding protein 1, UV-damaged DNA-binding factor, DDB1, XAP1, XPE-BF, HBV X-associated protein 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DDB1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 127 kDa |
Observed MW. | 127 kDa |
Uniprot ID: | Q16531, Q3U1J4, Q9ESW0 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis |
Background
This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.
Images
| Western blot analysis of DDB1 (GB112062) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
