Reactivity: | H,M,R & M,R |
Applications: | IHC/IF & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | DDX3Y rabbit polyclonal antibody |
Gene Name: | ATP-dependent RNA helicase DDX3Y |
Synonyms: | D1Pas1-related sequence 1, DEAD box protein 3, Y-chromosomal, DEAD-box RNA helicase DEAD2, mDEAD2, Ddx3y, D1Pas1-rs1, Dead2 |
Immunogen: | Recombinant protein corresponding to Mouse DDX3Y |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 73 kDa |
Observed MW. | 75 kDa |
Uniprot ID: | O15523, Q62095 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, brain |
Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process.
Images
Western blot analysis of DDX3Y (GB111540) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |