Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Diacylglycerol O-acyltransferase 2 |
Synonyms: | DGAT2, Diglyceride acyltransferase 2, HMFN1045, UNQ738/PRO1433 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DGAT2 |
Uniprot ID: | Q9DCV3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 44 kDa / 50 kDa |
Product Usage Information
WB | Human | 1: 800-1: 1500 | HeLa |
Background
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides. Functions also as an acyl-CoA retinol acyltransferase (ARAT). Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG).
Images
Western blot analysis of DGAT2 (GB114823) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |