Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | DIAPH1 rabbit polyclonal antibody |
Gene Name: | Protein diaphanous homolog 1 |
Synonyms: | Diaphanous-related formin-1, DRF1, Diaph1, DFNA1, diaphanous homolog 1, FLJ25265, hDIA1, LFHL1, p140DIA, Protein diaphanous homolog 1, Diap1 |
Immunogen: | Recombinant protein corresponding to Mouse DIAPH1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 139 kDa |
Observed MW. | 150 kDa |
Uniprot ID: | O60610, O08808, F1M775 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skin |
Background
The gene acts in a Rho-dependent manner to recruit PFY1 to the membrane. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. In hear cells, it may play a role in the regulation of actin polymerization in hair cells.
Images
Western blot analysis of Diap1 (GB111584) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |