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Anti-DISC1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DISC1 rabbit polyclonal |
Gene Name: | Disrupted in schizophrenia 1 homolog |
Synonyms: | C1orf136, DISC1, DISC1 long, disrupted in schizophrenia 1, KIAA0457, SCZD9 |
Immunogen: | Recombinant protein corresponding to Mouse DISC1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 93 kDa |
Observed MW. | 100 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | HeLa, U-251MG, U-87MG |
Background
DISC1, also named as KIAA0457, is identified as the sole gene whose ORF is truncated and cosegregates with major mental illnesses in a Scottish family. DISC1 may be implicated in psychiatric conditions in other populations than the unique Scottish family. It is involved in the regulation of multiple aspects of embryonic and adult neurogenesis. DISC1 is required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. It plays a role, together with PCNT, in the microtubule network formation.
Images
 | Western blot analysis of DISC1 (GB113550) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
