Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Delta-like protein 3 |
Synonyms: | pu, pudgy, delta like |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DLL3 |
Uniprot ID: | O88516 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 300-1: 600 | brain, spinal cord |
ICC/IF | Mouse, Rat | 1: 100-1: 400 | NIH-3T3 |
Background
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm .
|
Immunohistochemistry of paraffin embedded mouse brain using DLL3 (GB11321) at dilution of 1:300 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse spinal cord using DLL3 (GB11321) at dilution of 1:300 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using DLL3 (GB11321) at dilution of 1:300 (400x lens) |
| Immunohistochemistry of paraffin embedded rat spinal cord using DLL3 (GB11321) at dilution of 1:300 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse brain using DLL3 (GB11321) at dilution of 1:300 (400x lens) |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using DLL3(GB11321) at dilution of 1:100-1:400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
