Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | DLL4 rabbit polyclonal |
Gene Name: | Delta-like protein 4 |
Synonyms: | DLL4, hdelta2, AOS6, delta like canonical Notch ligand 4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DLL4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 100-1: 500 | heart, skeletal muscle |
IF | Mouse, Rat | 1: 200-1: 500 | heart, skeletal muscle |
Background
Involved in the Notch signaling pathway as Notch ligand . Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting . Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types ). During spinal cord neurogenesis, inhibits V2a interneuron fate.
Images
Immunohistochemistry analysis of paraffin-embedded rat heart using DLL4 (GB11322) at dilution of 1:200 |
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Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using DLL4 (GB11322) at dilution of 1:200 |
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Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using DLL4 (GB11322) at dilution of 1:200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |