Anti-DLL4 Rabbit pAb (100 μl)

Anti-DLL4 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB11322-100
Availability: In Stock
$259.00
-+
Reactivity: H,M,R    
Applications: WB    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

DLL4 rabbit polyclonal

Gene Name:

Delta-like protein 4

Synonyms:

DLL4, hdelta2, AOS6, delta like canonical

Notch ligand 4

Immunogen:

KLH conjugated Synthetic peptide

corresponding to Mouse DLL4

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Cell membrane

Uniprot ID:

Q9JI71, D3ZHH1




Product Usage Information

Applications

Species

Dilution

Positive tissue

IHC

Mouse, Rat

1: 100-1: 500

heart, skeletal muscle

IF

Mouse, Rat

1: 200-1: 500

heart, skeletal muscle




Background

Involved in the Notch signaling pathway as Notch ligand . Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting . Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types ). During spinal cord neurogenesis, inhibits V2a interneuron fate.




Images


Immunohistochemistry analysis of paraffin-embedded rat heart using DLL4 (GB11322) at dilution of 1:200

Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using DLL4 (GB11322) at dilution of 1:200

Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using DLL4 (GB11322) at dilution of 1:200




Storage

Storage Store at -20°C for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


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