Reactivity: | H & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | DMRTA2 rabbit polyclonal antibody |
Gene Name: | Doublesex- and mab-3-related transcription factor A2 |
Synonyms: | Doublesex- and mab-3-related transcription factor 5, Dmrta2, Dmrt5 |
Immunogen: | Recombinant protein corresponding to Mouse DMRTA2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 53 kDa |
Observed MW. | 53 kDa |
Uniprot ID: | Q96SC8, A2A9A2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | U-251MG |
IHC/IF | Mouse, Rat | 1: 600-1: 1400 | brain, colon, testis |
Background
DMRTA2 is a 542 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed testis, DMRTA2 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome.
Images
Western blot analysis of DMRTA2 (GB112559) at dilution of 1: 500 | |
Immunohistochemistry of paraffin embedded mouse brain using DMRTA2 (GB112559) at dilution of 1: 700 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse colon using DMRTA2 (GB112559) at dilution of 1: 700 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse testis using DMRTA2 (GB112559) at dilution of 1: 700 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using DMRTA2 (GB112559) at dilution of 1: 650 (400x lens) | |
Immunofluorescence of paraffin embedded mouse colon using DMRTA2 (GB112559) at dilution of 1: 650 (400x lens) | |
Immunofluorescence of paraffin embedded mouse testis using DMRTA2 (GB112559) at dilution of 1: 650 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |