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Anti-DNA Polymerase beta Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DNA Polymerase beta rabbit polyclonal antibody |
Gene Name: | DNA polymerase beta |
Synonyms: | POLB, DNA pol beta, DNA directed DNA polymerase beta |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse DNA Polymerase beta |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q8K409, P06766 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 4000 | brain, kidney, lung, ovary, testis |
Background
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Images
| Immunohistochemistry of paraffin embedded mouse brain using POLB (GB112436) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse ovary using POLB (GB112436) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry analysis of paraffin-embedded mouse ovary using POLB (GB112436) at dilution of 1: 4000 |
| Immunohistochemistry of paraffin embedded mouse testis using POLB (GB112436) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using POLB (GB112436) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat kidney using POLB (GB112436) at dilution of 1:1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat lung using POLB (GB112436) at dilution of 1:1000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse brain using POLB (GB112436) at dilution of 1:300 (400x lens) |
| Immunofluorescence of paraffin embedded mouse ovary using POLB (GB112436) at dilution of 1:300 (400x lens) |
| Immunofluorescence of paraffin embedded rat kidney using POLB (GB112436) at dilution of 1:300 (400x lens) |
| Immunofluorescence of paraffin embedded rat testis using POLB (GB112436) at dilution of 1:300 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
