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| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | DR1 rabbit polyclonal |
Gene Name: | Protein Dr1 |
Synonyms: | DR1, NC2, NC2 BETA, Negative cofactor 2 beta, Protein Dr1, TATA-binding protein-associated phosphoprotein, Down-regulator of transcription 1 |
Immunogen: | Recombinant protein corresponding to Mouse DR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 19 kDa |
Observed MW. | 19 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1500 | testis |
IHC | Mouse, Rat | 1: 3000-1: 6000 | brain, testis |
Background
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Images
| Western blot analysis of DR1 (GB113454) at dilution of 1: 1500 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using DR1 (GB113454) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using DR1 (GB113454) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded mouse testis using DR1 (GB113454) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded rat testis using DR1 (GB113454) at dilution of 1: 6000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
