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Anti-DREAM Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Calsenilin |
Synonyms: | A-type potassium channel modulatory protein 3, DRE-antagonist modulator, DREAM, Kv channel-interacting protein 3, KChIP3, Csen, Dream |
Immunogen: | Recombinant protein corresponding to Mouse DREAM |
Uniprot ID: | Q9QXT8 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 29 kDa / 29 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex, liver |
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | brain, heart |
Background
Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins).
Images
| Western blot analysis of DREAM (GB111918) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse heart using KCNIP3 (GB111918) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin embedded mouse brain using KCNIP3 (GB111918) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraffin embedded mouse brain using KCNIP3 (GB111918) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
