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| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | E3 ubiquitin-protein ligase DTX4 |
Synonyms: | deltex homolog 4 (Drosophila), Deltex4, DTX4, KIAA0937, Protein deltex 4, RING finger protein 155, RNF155 |
Immunogen: | Recombinant protein corresponding to Mouse DTX4 |
Uniprot ID: | Q6PDK8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 67 kDa / 67 kDa |
Product Usage Information
WB | Rat | 1: 800-1: 1500 | testis, kidney |
Background
Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.
Images
| Western blot analysis of DTX4 (GB115387) at dilution of 1: 1500 |
| Western blot analysis of DTX4 (GB115387) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
