Anti-DTYMK Rabbit pAb (100 μl)

Anti-DTYMK Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB112644-100
Availability: In Stock
$259.00
-+
Reactivity: M & H,M,R    
Applications: WB & IHC/IF    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

DTYMK rabbit polyclonal antibody

Gene Name:

Thymidylate kinase

Synonyms:

dTMP kinase, Dtymk, Tmk, CDC8, TMPK

Immunogen:

Recombinant protein corresponding to Mouse DTYMK

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Nucleus, Cytoplasm

Predicted MW.

24 kDa

Observed MW.

24 kDa

Uniprot ID:

P97930




Product Usage Information

Applications

Species

Dilution

Positive Sample

WB

Mouse

1: 500-1: 1000

kidney, brain

IHC/IF

Human, Mouse, Rat

1: 200-1: 1800

bladder, bladder cancer, colon cancer, kidney




Background

DTYMK is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.




Images

Western blot analysis of Dtymk (GB112644) at dilution of 1: 500

Immunohistochemistry of paraffin embedded mouse kidney using Dtymk (GB112644) at dilution of 1: 1800 (400x lens)

Immunohistochemistry of paraffin embedded rat kidney using Dtymk (GB112644) at dilution of 1: 1800 (400x lens)

Immunofluorescence of paraffin embedded human bladder cancer using Dtymk (GB112644) at dilution of 1: 650 (400x lens)

Immunofluorescence of paraffin embedded human colon cancer using Dtymk (GB112644) at dilution of 1: 650 (400x lens)

Immunofluorescence of paraffin embedded mouse bladder using Dtymk (GB112644) at dilution of 1: 650 (400x lens)

Immunofluorescence of paraffin embedded rat bladder using Dtymk (GB112644) at dilution of 1: 650 (400x lens)




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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